About 3421 Prytania Street
Historic Uptown Treasure — Prime Investment Opportunity! Step into a living piece of New Orleans history with this remarkable 107-year-old two-story gem, offering over 4,600 sq. ft. of space in one of Uptown’s most desirable locations. Perfectly positioned next to Touro Hospital and the thriving medical corridor, this property is just a block from St. Charles Avenue, the streetcar line, and the excitement of Mardi Gras parades. Currently configured as a four-unit multifamily residence (2/1, 1/1, efficiency, and an expansive 3/2 upstairs), this property’s HU-MU zoning allows for a wide range of commercial or residential uses, making it a rare and flexible investment opportunity. The spacious second-floor unit features three bedrooms, two baths, soaring ceilings, abundant natural light, oversized closets, and multiple living spaces—including a dining room, sitting area, and bonus room. The first floor offers three separate apartments that have historically provided steady rental income. Lovingly owned by the same family for over 80 years, this home is eligible for State and Federal Historic Tax Credits, enabling reimbursement of up to 45% of qualified renovation expenses. With a newer roof (2021) and located in an X Flood Zone, this property is full of long-term potential. Don’t miss your opportunity to own and reimagine this Uptown gem—whether you plan to restore its historic charm, convert it for mixed-use, or continue its residential legacy, the possibilities are endless. Open House Saturday, October 18, 2025 11:00 AM – 1:00 PM Contact us today to schedule your private tour and discover everything this extraordinary property has to offer!
Features of 3421 Prytania Street
| MLS® # | 2525628 |
|---|---|
| Price | $849,000 |
| Bedrooms | 7 |
| Bathrooms | 5.00 |
| Full Baths | 5 |
| Square Footage | 4,660 |
| Acres | 0.09 |
| Year Built | 1918 |
| Type | Multi-Family |
| Sub-Type | Traditional, Quadruplex |
| Status | Active |
Community Information
| Address | 3421 Prytania Street |
|---|---|
| City | New Orleans |
| County | Orleans |
| State | Louisiana |
| Zip Code | 70115 |
Amenities
| Parking | None |
|---|---|
| Is Waterfront | No |
| Has Pool | No |
| Pool | None |
Interior
| Heating | Central, Ductless, Wall Furnace |
|---|---|
| Cooling | CentralAir,Ductless,WallUnits |
| Fireplace | No |
| Has Basement | No |
Exterior
| Exterior | Brick, Frame, Wood Siding |
|---|---|
| Lot Description | City Lot, Rectangular Lot |
| Roof | Asphalt, Shingle |
| Construction | Brick, Frame, Wood Siding |
| Foundation | Raised |
Additional Information
| Days on Market | 17 |
|---|---|
| Foreclosure | No |
| Short Sale | No |
| RE / Bank Owned | No |
| HOA Fees | 0.00 |
| Listing Provided By | Villere Realty, LLC |